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目的了解医院感染高危科室的医务人员常见病毒感染情况。方法采用桥联酶标法直接检测８种呼吸道病毒抗原，用ＥＬＩＳＡ法检测血清两种病毒特异性抗体，分别对医护人员５４４人次、住院患者６９９人次和正常对照２５３人次，三组间进行比较与分析。结果患者组呼吸道病毒抗原阳性者明显高于医护组和正常组（Ｐ＜０．０５）而医护组与正常对照组无明显差异；柯萨奇Ｂ组病毒（ＣｏｘＢ）感染，医护组明显高于正常对照组（Ｐ＜０．０５）。巨细胞病毒（ＣＭＶ）感染ＩｇＧ三组间无差异，ＩｇＭ只有少数患者阳性，其它两组均阴性。结论呼吸道病毒感染在医患之间较易控制，而患者间容易交叉感染；医护人员感染ＣｏｘＢ的危险性（ＲＲ）为正常对照组的２．３５倍；ＣＭＶ对医护人员影响不大；医生与护士存在病毒感染的危险性无明显差异，故严格执行消毒隔离制度，加强无菌观念的培养二者同样至关重要
Objective To understand the prevalence of common viral infections among medical staff in hospital departments with high risk of infection. Methods Eight kinds of respiratory virus antigens were directly detected by the method of enzyme linked immunosorbent assay (ELISA). The serum specific antibodies against the two viruses were detected by ELISA. 544 medical staffs, 699 hospitalized patients and 253 normal controls were compared among the three groups analysis. Results The positive rate of respiratory virus antigen in patients was significantly higher than that in health care group and normal group (P <0.05), while there was no significant difference between health care group and normal control group. CoxB infection was significantly higher than that in health care group Normal control group (P <0.05). There was no difference among the three groups of cytomegalovirus (CMV) -infected IgG, only a few IgM patients were positive, and the other two groups were negative. Conclusions Respiratory virus infection is easy to control between patients and patients, but it is easy to cross-infection among patients. The risk of infection of CoxB by medical staff is 2.35 times of that of normal control group. CMV has little effect on medical staff; Nurses there is no significant difference in the risk of virus infection, so strict implementation of disinfection and isolation system, to strengthen the training of both the concept of aseptic life is equally crucial