论文部分内容阅读
目的了解广西孕产妇艾滋病、梅毒及丙型肝炎病毒感染现状,艾滋病防治知识知晓率及其感染艾滋病的危险因素,为孕产妇针对性干预策略的建立提供科学依据。方法将2011及2012年的4～8月确定为监测时间,监测期间就诊于广西35个孕产妇艾滋病监测哨点的所有孕产妇作为研究对象,对孕产妇的人口学特征、艾滋病相关知识、吸毒及性行为等进行问卷调查,并采集3～5ml静脉血进行HIV、梅毒及HCV抗体检测,应用SPSS20.0进行数据处理与分析。结果 (1)共调查了28 078名孕产妇,回收有效问卷26 883份,调查问卷的有效应答率为95.74%。监测期间,采集血样28 077份,HIV感染率为0.10%(29/28 077)、梅毒感染率为0.81%(227/28 077)、HCV感染率为0.23%(64/28 077)。(2)孕产妇艾滋病知识的总体知晓率为88.43%,对艾滋病的非传播途径知晓率为77.31%～86.44%,对三大传播途径的知晓率为88.93%～97.14%。(3)单因素分析显示:文化程度、丈夫吸毒、有丈夫以外性伙伴、丈夫艾滋病/性病以及HCV阳性是感染HIV的危险因素;(4)多因素Logistic回归分析显示:小学及以下文化程度感染艾滋病的风险是其他文化程度者的4.40倍(P=0.01,95%CI=(1.37,14.12)),丈夫为艾滋病或性病患者的孕产妇感染艾滋病的风险是丈夫为非艾滋病非性病者的152.57倍(P=0.01,95%CI=(49.06,474.47))。结论广西孕产妇HIV和HCV感染率尚处于较低水平,梅毒感染率略高;需重点关注丈夫吸毒、丈夫为艾滋病患者、多男性伴、HCV阳性以及文化程度在小学及以下的孕产妇,加强随访和HIV检测是减少垂直传播的重要手段。
Objective To understand the status quo of AIDS, syphilis and hepatitis C virus infection among pregnant women in Guangxi, the awareness rate of HIV / AIDS and AIDS risk factors, and provide a scientific basis for the establishment of targeted intervention strategies for pregnant women. Methods From April to August of 2011 and 2012, the monitoring time was defined as the monitoring time. All the pregnant women who visited the 35 sentinel HIV / AIDS sentinel clinics in Guangxi during the monitoring period were selected as the research objects. The demographic characteristics, AIDS-related knowledge, And sexual behavior such as questionnaires, and collected 3 ~ 5ml venous blood HIV, syphilis and HCV antibody detection, application SPSS20.0 data processing and analysis. Results (1) A total of 28 078 pregnant women were surveyed, 26 883 valid questionnaires were recovered, and the effective response rate of the questionnaire was 95.74%. During the monitoring period, 28,077 blood samples were collected, the HIV infection rate was 0.10% (29/28 077), the syphilis infection rate was 0.81% (227/28 077) and the HCV infection rate was 0.23% (64/28 077). (2) The overall awareness of HIV / AIDS among pregnant women was 88.43%, the awareness rate of non-transmission of AIDS was 77.31% -86.44%, and the awareness of the three routes of transmission was 88.93% -97.14%. (3) Univariate analysis showed that: education level, husband’s drug abuse, husband’s sex partner, husband’s HIV / AIDS and HIV positive were the risk factors of HIV infection; (4) Multivariate logistic regression analysis showed that: The risk of AIDS was 4.40 times that of other people with education level (P = 0.01,95% CI = (1.37,14.12)). The risk of HIV infection for pregnant women who were husbands living with AIDS or STDs was 152.57 Fold (P = 0.01, 95% CI = (49.06, 474.47)). Conclusion The prevalence of HIV and HCV among pregnant women in Guangxi is still low and the infection rate of syphilis is slightly higher. It is necessary to pay more attention to the drug abuse of husbands, husbands with HIV / AIDS, multiple male partners, HCV positive and pregnant women with primary school education or below, Follow-up and HIV testing are important ways to reduce vertical transmission.