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为探讨嗜酸性阳离子蛋白（ＥＣＰ）与慢性支气管炎急性发作期的关系，对１８例慢支急发期患者和１０例缓解期患者采用支气管肺泡灌洗术，并分别测定其支气管肺泡灌洗液（ＢＡＬＦ）和血清的ＥＣＰ水平进行比较。结果急发期ＢＡＬＦ中的ＥＣＰ水平显著高于缓解期对照组，而两组血清ＥＣＰ水平无显著差异。提示嗜酸性粒细胞（ＥＯＳ）参与了慢支急发期气道炎症过程。
To explore the relationship between eosinophilic cationic protein (ECP) and acute exacerbation of chronic bronchitis, bronchoalveolar lavage (BALF) was performed in 18 patients with chronic bronchitis and 10 patients with remission, and bronchoalveolar lavage fluid (BALF) and serum ECP levels were compared. Results The level of ECP in BALF at the acute stage was significantly higher than that in the control group at remission, but there was no significant difference between the two groups in serum ECP level. Eosinophils (EOS) are involved in the airway inflammation process in patients with chronic bronchitis.