结直肠癌缺失基因 ,即 DCC基因 ,是近年来发现的大肠癌中一个重要的肿瘤抑制基因 ,其在妇科肿瘤中的作用也日益受到研究者的重视 ,但有关此方面的研究国内尚未见报道。本文就 DCC基因的分子生物学特性、作用机制、与妇科肿瘤关系的研究等方面作一简要综述 Colorectal cancer deletion gene, DCC gene, is an important tumor suppressor gene in colorectal cancer discovered in recent years, and its role in gynecologic oncology has also been paid more and more attention by researchers. However, there is no report about the study of this gene in China . In this paper, a brief overview of the molecular biological characteristics of DCC gene, the mechanism of action, and the relationship between gynecological cancer and other aspects