论文部分内容阅读
目的:探讨异位妊娠药物保守治疗的最佳治疗方案。方法:按用药方案不同,将保守治疗的早期未破裂型异位妊娠患者106例分为3组,A组:自拟中药方+口服米非司酮;B组:口服米非司酮+血府逐瘀口服液;C组:仅口服米非司酮,必要时重复使用。比较各组的治疗效果。结果:A、B、C 3组的有效率分别为94.4%、76.7%、72.5%,A组与B、C组比较差异有统计学意义(P<0.05)。血β-HCG下降速度:A组显著优于B、C组(P<0.05),B组和C组比较差异无统计学意义(P>0.05);腹痛和阴道流血消失(2周内):A组明显优于C组(P<0.05),B组和C组比较差异亦有统计学意义(P<0.05),A组和B组比较差异无统计学意义(P>0.05);包块缩小≥50%(3周内):A组明显优于C组(P<0.01),B组和C组比较差异亦有统计学意义(P<0.05),A组和B组比较差异无统计学意义(P>0.05);随访输卵管情况:A组输卵管复通率高于C组(P<0.05);A组与B组比较及B组与C组比较差异均无统计学意义(P>0.05)。结论:自拟中药方联合口服米非司酮可优势互补,协同快速杀胚,减少重复用药,促进包块吸收,缩短病程,有利于保持输卵管完整性。
Objective: To explore the best treatment for conservative treatment of ectopic pregnancy. Methods: 106 patients with early unruptured ectopic pregnancy who underwent conservative treatment were divided into 3 groups according to different dosage regimen. Group A: self-made Chinese prescription + oral mifepristone; group B: oral mifepristone + blood House Zhuyu oral solution; C group: only oral mifepristone, if necessary, re-use. Compare the treatment effect of each group. Results: The effective rates of group A, B and C were 94.4%, 76.7% and 72.5%, respectively. There was significant difference between group A and group B and C (P <0.05). The decline rate of β-HCG in blood was significantly higher in group A than in group B and C (P <0.05), but there was no significant difference between group B and group C (P> 0.05); The disappearance of abdominal pain and vaginal bleeding (within 2 weeks) A group was significantly better than C group (P <0.05), B group and C group was also significantly different (P <0.05), A group and B group was no significant difference (P> 0.05) (P <0.01). There was also a significant difference between group B and group C (P <0.05). There was no significant difference between group A and group B (P> 0.05). The incidence of tubal follow-up was significantly higher in group A than in group C (P <0.05). There was no significant difference between group A and group B and group B and group C (P> 0.05). CONCLUSION: Self-made Chinese herbal prescription combined with oral mifepristone can complement each other well, kill syphilis rapidly, reduce repeated medication, promote the absorption of mass and shorten the course of disease, which is beneficial to maintain the integrity of fallopian tube.