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我们通过观察选择性环氧合酶 2 (COX 2 )抑制剂塞莱昔布对酒精性肝损伤 (ALD)大鼠中谷胱甘肽 S转移酶 (GST)和超氧化物歧化酶 (SOD)活性以及丙二醛 (MDA)水平的影响 ,了解COX 2对ALD大鼠氧化与抗氧化系统的作用 ,以探索它们之间的关系。一、实验动物与模型5 8只Wistar雄性大鼠
We observed the effects of selective cyclooxygenase 2 (COX 2) inhibitor celecoxib on glutathione S-transferase (GST) and superoxide dismutase (SOD) activity in alcoholic liver injury (ALD) rats (MDA) and the effect of COX 2 on the oxidative and anti-oxidative system in ALD rats to explore the relationship between them. First, experimental animals and models 58 male Wistar rats