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目的探讨联合检测血清中α-L岩藻糖苷酶(AFU)与HS-CRP在妊娠糖尿病(GDM)中的临床意义。方法对60例妊娠糖尿病患者分为控制良好(A组)、坏(B组)两组各30例和20例健康妊娠妇女(对照组)分别进行空腹血糖、AFU和HS-CRP的检测。结果妊娠糖尿病患者A组血清中AFU及HS-CRP的值明显高于B组,且AFU及HS-CRP成正相关,B组与对照组无明显差异。结论在糖尿病时联合检测AFU与HS-CRP对血糖筛查正常、糖耐量正常及异常且对病情起到监测作用,可作为临床诊断、监测及用药的客观指标。
Objective To investigate the clinical significance of combined detection of α-L-fucosidase (AFU) and HS-CRP in gestational diabetes mellitus (GDM). Methods 60 cases of gestational diabetes mellitus were divided into control group (group A), group B (30 cases) and healthy control group (group 20). The levels of fasting blood glucose, AFU and HS-CRP were measured respectively. Results The serum values of AFU and HS-CRP in group A with gestational diabetes mellitus were significantly higher than those in group B, and there was a positive correlation between AFU and HS-CRP. There was no significant difference between group B and control group. Conclusion The combined detection of AFU and HS-CRP during diabetes mellitus has normal, normal glucose tolerance and abnormal blood glucose monitoring, which can be used as an objective indicator of clinical diagnosis, monitoring and medication.