深圳市福田区2007—2009年急性弛缓性麻痹病例流行病学分析

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目的为进一步做好急性弛缓性麻痹(AFP)病例监测,巩固无脊髓灰质炎(脊灰)成果。方法对深圳市福田区2007—2009年AFP病例的流行病学特征及监测系统运转情况进行描述性流行病学分析及统计分析。结果福田区2007—2009年报告AFP病例43例,年龄分布结果差异有统计学意义(χ2=19.7125,P<0.01)。我区<15岁儿童非脊灰AFP病例报告发病率3年分别为1.47/10万、1.33/10万、1.21/10万,AFP病例监测系统各项指标均达到要求。合格粪便标本采集率为95.3%,分离到Ⅰ、Ⅱ、Ⅲ型脊灰病毒各一株,为疫苗株;非脊灰肠道病毒分离率为4.6%。2007—2009年福田区OPV基础免疫报告接种率分别为99.5%、99.0%、100%。2008年3—9月开展以流动儿童为主的查漏补种活动,摸底调查应补服OPV2190人份,共补服2184人份。结论做好常规免疫和AFP病例合格粪便标本的采集,继续保持AFP病例监测系统敏感性,是无脊灰证实阶段重要的工作。 Objective To further monitor cases of acute flaccid paralysis (AFP) and consolidate poliomyelitis-free (polio) outcomes. Methods Descriptive epidemiological analysis and statistical analysis were performed on the epidemiological characteristics of AFP cases and the monitoring system operation in Futian District, Shenzhen City from 2007-2009. Results Forty-three cases of AFP were reported in Futian District in 2007-2009. There was significant difference in age distribution (χ2 = 19.7125, P <0.01). The incidence of non-polio AFP cases in children aged <15 years in our district was 1.47 / lakh, 1.33 / lakh and 1.21 / lakh, respectively. The indicators of AFP case monitoring system met the requirements. The collection rate of qualified stool samples was 95.3%. One strain of type Ⅰ, Ⅱ and Ⅲ poliovirus was isolated, which was a vaccine strain. The isolation rate of non-polio enterovirus was 4.6%. 2007-2009 Futian District OPV basic immunization coverage rates were 99.5%, 99.0%, 100%. March-September 2008 to carry out leaky and replanting activities mainly to mobile children, thoroughly survey should complement OPV 21,900 people, a total of 2184 serving people. Conclusion The routine immunization and collection of qualified stool specimens for AFP cases continue to maintain the sensitivity of monitoring system of AFP cases, which is an important work in the stage of polio-free confirmation.
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