以二乙醇胺和2,3-二氯苯胺为原料改进了一锅法合成1-(2,3-二氯苯基)哌嗪盐酸盐,产品纯度>99.5%,杂质<0.1%,且反应时间短,成本低,无污染气体产生,适于放大生产。 One-pot synthesis of 1- (2,3-dichlorophenyl) piperazine hydrochloride was improved by using diethanolamine and 2,3-dichloroaniline as raw materials. The purity of the product was more than 99.5% and the impurity was less than 0.1% Short time, low cost, pollution-free gas generation, suitable for amplification of production.