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目的:分析曲安奈德局部注射治疗桥本甲状腺炎的疗效。方法:从我院2010年3月~2012年3月治疗的桥本甲状腺患者中选取72例进行研究,将全部患者分成对照组和研究组,对照组患者采用左甲状腺素钠片口服治疗,研究组则采用曲安奈德局部注射治疗。对2组患者甲状腺腺体大小变化情况进行观察,对比2组患者治疗后TPOAb、TgAb。结果:治疗后研究组患者TPOAb、TgAb下降幅度较大,明显低于对照组(p<0.05),同时研究组患者的甲状腺腺体体积缩小也比对照组多(p<0.05)。结论:在桥本甲状腺炎的治疗中应用局部注射曲安奈德能有效控制甲状腺局部免疫反应,获得较好的治疗效果,且减少了不良反应的发生,临床值得推广。
Objective: To analyze the curative effect of local injection of triamcinolone acetonide on Hashimoto’s thyroiditis. Methods: Seventy-two patients were selected from Hashimoto’s thyroiditis treated in our hospital from March 2010 to March 2012. All patients were divided into control group and study group. Patients in the control group were treated with levothyroxine sodium tablets. Group was treated with triamcinolone local injection. The changes of thyroid gland size in two groups were observed, and the TPOAb and TgAb in two groups were compared. Results: After treatment, the decrease of TPOAb and TgAb in the study group was significantly lower than that in the control group (p <0.05), and the volume of thyroid gland in the study group was also smaller than that in the control group (p <0.05). Conclusion: The local injection of triamcinolone acetonide in the treatment of Hashimoto’s thyroiditis can effectively control thyroid local immune response, get better therapeutic effect, and reduce the incidence of adverse reactions, the clinical worth promoting.