高同型半胱氨酸(Hcy)血症是动脉血栓和动脉粥样硬化所致的心脑血管病的独立危险因子。近年来对防治高Hcy血症的研究取得了一些进展,尤其是在高Hcy血症的发病机制方面,以及内源性高Hcy血症拮抗剂牛磺酸、硫化氢、合成谷胱甘肽、金属硫蛋白以及药物叶酸、维生素B12、维生素B6、维生素B2以及甜菜碱等防治方面,均有一定的进展。 Hyperhomocysteinemia is an independent risk factor for cardiovascular and cerebrovascular diseases caused by arterial thrombosis and atherosclerosis. In recent years, some progress has been made in the prevention and treatment of hyperhomocysteinemia, especially in the pathogenesis of hyperhomocysteinemia, as well as the effects of endogenous hyperhomocysteinemic antagonists such as taurine, hydrogen sulfide, synthetic glutathione, Metallothionein and drug folic acid, vitamin B12, vitamin B6, vitamin B2 and betaine prevention and treatment, have made some progress.