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目的 为了探讨晚发性维生素K缺乏症患儿的血钙问题.方法 对22例晚发性维生素 K缺乏症患儿进行血钙及碱性磷酸酶浓度测定.结果 显示22例的血钙浓度均有不同程度的降低,其中<155mmol/L8例,～1.75mmol/L9例,～2mmol/L4例,2.25mmoL/L1例.测定10例病例的碱性磷酸酶,有9例升高.结论 晚发性维生素K缺乏症常伴有低钙血症,且合并有维生素D缺乏.认为晚发性维生素K缺乏症不仅是单纯的维生素K缺乏,可能还伴有其它脂溶性维生素的不足.维生素D缺乏性手足搐搦与晚发性维生素K缺乏所致颅内出血可能同时并存或先后发生,治疗时应两者兼顾.
Objective To investigate the serum calcium in children with late onset vitamin K deficiency.Methods Serum calcium and alkaline phosphatase concentrations were measured in 22 children with late onset vitamin K deficiency.The results showed that all 22 patients had serum calcium There were 8 cases in <155mmol / L, 9 cases in ~ 1.75mmol / L, 2mmol / L in 4 cases and 2.25mmoL / L1 cases.Of the 10 cases, alkaline phosphatase was detected in 9 cases.Conclusions Deficiency of vitamin K often accompanied by hypocalcemia, and combined with vitamin D deficiency that delayed vitamin K deficiency is not only a simple lack of vitamin K, may also be associated with the lack of other fat-soluble vitamins Vitamin D Lack of tetany and late onset of vitamin K deficiency caused by intracranial hemorrhage may occur simultaneously or in succession, treatment should be both.