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目的了解某综合医院多药耐药菌(MDROs)医院感染的控制效果。方法对2005年1月-2010年12月某院所临床培养出MDROs的住院患者进行调查;2008年7月-2010年12月采取前瞻性调查方法,并对感染及定植患者采取组合式(Bundle)控制措施,包括手卫生、隔离、戴手套、穿隔离衣等;2005年1月-2008年7月采取回顾性调查方法,但其调查内容与调查表、诊断标准等与前瞻性调查方法相同,分析综合控制措施的效果。结果 2005年1月-2010年12月共收治243 744例患者,3 084 182患者住院日,发生2279例次MDROs感染,包括医院发病的感染(HOI)1025例次,占44.98%,社区发病的感染(COI)1254例次,占55.02%;多元线性回归分析显示,在排除MDROs-HOI的影响后,采取控制措施可有效降低MDROs-HOI感染率,以外科控制效果最为显著。结论采取预防控制措施可有效防止MDROs在医院内的传播。
Objective To understand the control effect of multidrug-resistant bacteria (MDROs) hospital infection in a general hospital. Methods Inpatients with MDROs who underwent clinical training in a hospital from January 2005 to December 2010 were investigated. From July 2008 to December 2010, a prospective investigation was carried out. Patients with infection and colonization were treated with a combination of Bundle ) Control measures, including hand hygiene, isolation, wearing gloves, gown, etc .; January 2005 -2008 July retrospective survey method, but the survey content and questionnaires, diagnostic criteria and the same as the prospective investigation method , Analyze the effect of comprehensive control measures. Results A total of 243 744 patients and 3 084 182 patients were admitted to hospital from January 2005 to December 2010. A total of 2,279 MDROs infections occurred, including 1025 HOI cases (44.98%) and community morbidity Infected (COI) 1254 cases, accounting for 55.02%; multivariate linear regression analysis showed that the exclusion of the impact of MDROs-HOI, the control measures can effectively reduce the MDROs-HOI infection rate, the most obvious surgical control. Conclusion Prevention and control measures can effectively prevent the spread of MDROs in hospitals.