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目的:探讨利用糖皮质激素联合抗生素治疗老年慢性阻塞性肺气肿的临床疗效。方法:选取2012年5月至2013年5月于我院收治的60例慢性阻塞性肺气肿患者为研究对象,随机分为两组,每组30例。两组均接受常规吸氧、祛痰、支气管扩张和抗生素治疗,观察组再给予泼尼松进行联合治疗。结果:两组患者在治疗后均显示PaO2和PaCO2的显著改善(P<0.05)。观察组疗效显著高于对照组,具有统计学差异。结论:抗生素联合糖皮质激素治疗老年慢性阻塞性肺气肿能够显著提高临床疗效,这种联合用药值得在临床上进行推广。
Objective: To explore the clinical efficacy of glucocorticoid combined with antibiotics in the treatment of senile chronic obstructive pulmonary emphysema. Methods: Sixty patients with chronic obstructive pulmonary emphysema admitted to our hospital from May 2012 to May 2013 were selected and randomly divided into two groups (n = 30 in each group). Both groups received conventional oxygen, expectorant, bronchiectasis and antibiotics, the observation group and then treated with prednisone. Results: Both groups showed significant improvements in PaO2 and PaCO2 after treatment (P <0.05). Observation group was significantly higher than the control group, with statistical differences. Conclusion: The combination of antibiotics and glucocorticoids in the treatment of senile chronic obstructive pulmonary emphysema can significantly improve the clinical curative effect. This combination therapy is worth popularizing clinically.