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玫瑰痤疮是一种慢性复发性炎症性皮肤疾病,其发病机制可能与天然免疫功能异常、神经脉管调节功能异常、微生物感染、内分泌紊乱、遗传、皮肤屏障功能障碍等因素相关,治疗以口服米诺环素、多西环素、羟氯喹、卡维地洛、异维A 酸,外用甲硝唑、钙调磷酸制剂、壬二酸霜剂、伊维菌素、过氧化苯酰凝胶及联合激光、手术等治疗为主,笔者对其治疗和发病机制进行综述.“,”Acne vulgaris is a chronic and recurrent inflammatory skin disease. It is reported that the pathogenesis and aggravating factors of rosacea may be related to natural immune defense, neurovascular dysregulation, microorganism infection, endocrine disorder, heredity, skin barrier dysfunction and so on. Treatment mainly include oral medicine such as minocycline, doxycycline, hydroxychloroquine, carvedilol, isotretinoin, and topical agents such as metronidazole, calcineurin inhibitors, azelaic acid, ivermectin, benzoyl peroxide or combined with laser therapy and surgical operation, etc. This article reviews the latest treatments and the pathogenesis of acne rosacea.