1955年Conn首先定义并报告了原发性醛固酮增多症(prim ay aldosteron ism,PA),它是指由于肾上腺皮质本身病变,分泌过多的醛固酮,导致水钠潴留、血容量扩张、肾素-血管紧张素系统活性受抑制所产生的综合征。随着诊疗水平的不断提高,该病在高血压人群,特别是难治性高血压患者的检 1955 Conn first defined and reported the primary aldosteronism (prim ay aldosteron ism, PA), which refers to the adrenal cortex itself lesions, excessive secretion of aldosterone, leading to Shuinazhuliu, blood volume expansion, renin - Syndromes resulting from the inhibition of angiotensin system activity. With the continuous improvement of the level of diagnosis and treatment, the disease in hypertensive population, especially in patients with refractory hypertension