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目的通过单采血小板及冷沉淀凝血因子在产科弥散性血管内凝血(DIC)患者抢救过程中的应用,分析其治疗效果。方法在单采血小板及冷沉淀凝血因子输注前后各抽取产科DIC患者静脉血5ml,分别测定凝血酶原时间(PT)和出、凝血时间(CT、BT),血小板计数及纤维蛋白定量。结果产科DIC患者输注单采血小板及冷沉淀凝血因子后,PT、CT、BT明显缩短,血小板计数及纤维蛋白定量显著增多。结论产科DIC患者早期及时适量输注单采血小板及冷沉淀凝血因子可以有效阻止DIC的继续发展,重建自身的凝血机制,获得了良好的止血效果,为其他治疗措施提供了时机。
Objective To evaluate the therapeutic effect of apheresis platelets and cryoprecipitated coagulation factors in the treatment of patients with obstetric disseminated intravascular coagulation (DIC). Methods Before and after the apheresis platelets and cryoprecipitated coagulation factor infusion, 5ml venous blood was collected from obstetric patients with DIC. The prothrombin time (PT), clotting time (CT, BT), platelet count and fibrin quantitation were measured. Results The obstetric DIC patients were transfused with apheresis and cryoprecipitated coagulation factors, PT, CT, BT significantly shortened, platelet count and fibrin quantitative significantly increased. Conclusions Early timely delivery of apheresis platelets and cryoprecipitated coagulation factors in obstetric patients with DIC can effectively prevent the continuous development of DIC, rebuild their own coagulation mechanism and obtain good hemostatic effect, which provides an opportunity for other treatment measures.