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目的:对鼻咽癌’92分期和UICC分期(草案,1996)进行比较。材料与方法:411例初次放射治疗的鼻咽癌病例资料纳入研究,重新分期,比较两分期的优缺点,生存分析计算5年生存率、无复发生存率和无远处转移生存率等。一致性和相关性评价的指标有Kappa值和Perason系数。结果:’92分期T和N的划分比较合理,而UICC分期的T2和T3的生存率与无鼻咽复发生存率接近或交叉,N2与N3的生存率和无远处转移生存率接近。两分期间的一致率为72%,Kappa值为0.6,Pcarson系数为0.82。结论:’92分期的T与N分期更为合理,其划分考虑了肿瘤侵犯程度等因素,能更好地预测预后和指导治疗,分期组合的规律性好,易于推广。两个分期间存在一定的一致性和相关性。
OBJECTIVE: To compare the ’92 staging and UICC staging of nasopharyngeal carcinoma (draft, 1996). MATERIALS AND METHODS: A total of 411 cases of nasopharyngeal carcinoma treated with initial radiotherapy were included in the study. The patients were divided into two groups according to their pros and cons. Survival analysis was used to calculate the five-year survival rate, recurrence-free survival rate, and distant metastasis-free survival rate. The indicators of consistency and relevance evaluation are Kappa value and Perason coefficient. Results: The classification of T stage and N stage was more reasonable in 92 cases, while the survival rates of T2 and T3 in UICC stage were close to or crossed with those without nasopharyngeal recurrence. The survival rates of N2 and N3 were similar to those without distant metastasis. The agreement rate was 72% for both periods, with a Kappa value of 0.6 and a Pcarson coefficient of 0.82. Conclusions: The T stage and N stage of ’92 staging are more reasonable. The division of T stage and T stage consider the degree of tumor invasion, which can better predict prognosis and guide treatment. The staging of staging is good and easy to popularize. There is some consistency and relevance between the two sub-periods.