贝诺酯(又名扑炎痛,benorilate)引起的急性肝脏损害不多见,现将我们遇到的1例报道如下。 患者女,24yr。因发烧、咳嗽,咯白色泡沫痰4d入院。平素体健,既往无肝病史,否认肝炎接触史及药物过敏史。入院后经查体、胸片和实验室检查,临床诊断为急性支气管炎。静脉滴注青霉素480万U/d,治疗4d后呼吸道症状基本消失,体温恢复正常,双肺干湿罗音消失。因出现游走性关节疼痛,以大关节为主,血沉55mm/h,考虑伴风湿性关节炎,加服贝诺酯1g tid,3d后患者感乏力,肝区不适,尿液黄。查体发现皮肤及巩膜黄染、肝肋下1cm,微触 Benoxylate (also known as Puffy, benorilate) caused by acute liver damage is rare, now we have encountered a case reported as follows. Patient female, 24yr. Due to fever, cough, slightly white foam sputum 4d admission. Usually physical health, past no history of liver disease, history of exposure to hepatitis and drug allergy history. After admission by the physical examination, chest X-ray and laboratory tests, the clinical diagnosis of acute bronchitis. Intravenous infusion of penicillin 4.8 million U / d, respiratory symptoms disappeared after 4 days of treatment, body temperature returned to normal, lung wet and dry rales disappeared. Because of the emergence of migratory joint pain, the main joint, ESR 55mm / h, consider rheumatoid arthritis, plus clothing Benone ester 1g tid, 3d patients feel weak, liver discomfort, urine yellow. Examination found that the skin and sclera yellow dye, liver ribs 1cm, micro-touch