作者系统复习了320例普通急性淋巴细胞白血病患儿的初诊骨髓片,嗜苯胺蓝颗粒直径大于0.5μm的原始细胞超过5%者算作阳性病例。作者发现,20例(7%)为阳性病例,其中9例(3%)颗粒淋巴细胞超过10%。20例患儿中19例经免疫学检测具有la和C-ALL抗原及末端脱氧核苷酸转移酶阳性。大多数颗粒淋巴细胞的酸性磷酸酶染色强阳性,糖原染色阳性,苏丹黑染色阴性。颗粒性急性淋巴细胞白血病是一种变异型,多见于普通型急淋,尤其是男孩及 The author system reviewed 320 newly diagnosed bone marrow smears from children with normal acute lymphoblastic leukemia. Positive aniline blue particles with a diameter greater than 0.5 μm were counted as positive. The authors found that 20 (7%) were positive cases, of which 9 (3%) had more than 10% granular lymphocytes. Nineteen of the 20 patients had immunogenicity with la and C-ALL antigens and positive terminal deoxynucleotidyl transferase. Most of the granular lymphocytes were strongly positive for acid phosphatase staining, positive for glycogen staining, and negative for Sudan black staining. Granular acute lymphoblastic leukemia is a variant, more common in ordinary acute shower, especially boys and