Role of surgery and transplantation in the treatment of hepatic metastases from neuroendocrine tumor

来源 :World Journal of Gastroenterology | 被引量 : 0次 | 上传用户:xxj8880430
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
Neuroendocrine tumors(NET) are a heterogeneous group of cancers, with indolent behavior. The most common primary origin is the gastro-intestinal tract but can also appear in the lungs, kidneys, adrenals, ovaries and other organs. In general, NET is usually discovered in the metastatic phase(40%-80%). The liver is the most common organ involved when metastases occur(40%-93%), followed by bone(12%-20%) and lung(8%-10%).A number of different therapeutic options are available for the treatment of hepatic metastases including surgical resection, transplantation, ablation, trans-arterial chemoembolization, chemotherapy and somatostatin analogues. Recently, molecular targeted therapies have been used, usually in combination with other treatment options, to improve outcomes in patients with metastases. This article emphasizes on the role of surgery in the treatment of liver metastases from NET. The most common primary origin is the gastro-intestinal tract but can also appear in the lungs, kidneys, adrenals, ovaries and other organs. In general, NET is usually discovered in the metastatic phase (40% -80%). The liver is the most common organ involved when metastases occur (40% -93%) followed by bone (12% -20% ) A number of different therapeutic options are available for the treatment of hepatic metastases including surgical resection, transplantation, ablation, trans-arterial chemoembolization, chemotherapy and somatostatin analogues. Recently, molecular targeted therapies have been used, usually in combination with other treatment options , to improve outcomes in patients with metastases. This article emphasizes on the role of surgery in the treatment of liver metastases from NET.
其他文献
本文利用量纲分析方法对现有的射弹侵彻混凝土深度预估公式的特点及不足进行了分析讨论,指出了合理的预估公式所应包含的相似准则并据此依赖大量的试验拟合出了新的经验公式,
采用MOCL(Mark On Cell Line)分界面跟踪算法,用二维多流体网格法的欧拉程序,对卵型头和平头动能弹侵彻混凝土平靶的过程进行了数值模拟研究,并与卵型头弹侵彻的试验结果进行
本文首先初步总结了目前关于金属材料动态起裂韧性实验测试的研究进展.然后根据金属材料的静态断裂韧性、动态起裂韧性及其相关影响因素的研究,进一步讨论材料动态起裂韧性的
Objective: To determine the clinicopathological characteristics, and evaluate the appropriate extent of lymph node dissection in distal gastric cancer patients
本文讨论了射流为理想不可压缩介质时,不同射流速度分布情况下的射流侵彻深度的理论公式.
本文利用数值模拟方法对成层式抗侵彻结构组合形式进行了研究,指出射弹侵彻过程中的能量消耗与过程密切相关,即使用相同的材料组成层式抗侵彻结构,如果组合顺序不一样,侵彻效
本文介绍了国外制导炸弹和导弹钻地武器的型号、用途、性能及改进.
本文应用粗估计算和二维弹塑性数值模拟两种方法对一些动能弹模型及其缩比模型侵彻混凝土厚靶问题进行了探讨.主要研究了穿深与缩比量、初始碰速、弹长径比及弹头壳体材料等
对环形切割随进射流对海洋中复合靶的侵彻进行数值模拟.对第一级环形切割装置的装药点火后起爆后对第二级聚能射流装置的安全问题进行了论证.数值模拟结果表明,第一级点火后,
本课题应用混合物迭加原理计算出混凝土冲击绝热拟合线,与通过实验得到它的冲击绝热拟合线;实验样品混凝土计算拟合式和实验测定的线性拟合式两者吻合程度是令人满意的.