共聚焦激光内镜的诞生标志着内镜检查的一个新的时代的到来,预示着内镜检查将从宏观走向微观,从表层走向深层,从影像走向机能。下面从共聚焦激光内镜的基本原理、结构、应用、展望等方面对其做一初步综述。一、共聚焦激光内镜的基本原理共聚焦激光内镜是将共聚焦激光显微镜整合于传统电子内镜之上,因此其成像的基本原理等同于共聚焦激光显微镜(confocal laser scanning microscope,CLSM),即利用激光扫描技术,照明光由光源经光源针孔再聚焦,在被观察的物体中的某一深度形成一个光点,其反射光经聚焦后需通过观察针孔才能到达成像面,被观察的物体中高于或低于焦点平面 Confocal laser endoscopy marks the birth of a new era of endoscopy, indicating that endoscopy will move from macro to micro, from the surface to the deeper, from the image to function. The following from the confocal laser endoscopy basic principles, structure, application, prospects and so on to make a preliminary review. First, the principle of confocal laser endoscopy confocal laser endoscopic confocal laser microscopy is integrated on the traditional electronic endoscopy, the basic principle of its imaging is the same as confocal laser scanning microscopy (confocal laser scanning microscope, CLSM) , That is, the use of laser scanning technology, the illumination light from the light source through the pinhole re-focus, was observed in a certain depth of the object to form a light spot, the reflected light after focusing through the pinhole to reach the imaging surface was The observed object is above or below the focal plane