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近年来，国内外对端粒酶作为肿瘤治疗靶分子的可能性，尤其对测定端粒酶诊断肿瘤的潜在价值，都非常关心。为了满足读者的需要，特在本期发表了这篇有关端粒酶的综述，读者可结合本期简报栏中一组国内研究端粒酶的报道，综观国内外的研究现况。必须指出，虽然端粒酶在肿瘤组织中检出率很高，但由于存在非特异性，要应用于肿瘤的临床诊断还有一段距离，仍需从定性和定量方面进行广泛扎实的观测研究，弄清假阳性的成因，排除各种取标本方式对检测结果的影响，进一步明确与临床的相关性。
In recent years, the possibility of using telomerase as a target for tumor treatment at home and abroad has been of great concern, especially for the measurement of the potential value of telomerase in the diagnosis of tumors. In order to meet the needs of readers, this review of telomerase was published in this issue. Readers can combine the reports of a group of domestic studies on telomerase in the current bulletin and review the current research status at home and abroad. It must be pointed out that although the detection rate of telomerase in tumor tissue is high, due to its non-specificity and to be applied to the clinical diagnosis of tumors, there is still a long way to go, and it is still necessary to carry out extensive and solid observational research from qualitative and quantitative aspects. The cause of clearing false positives was to eliminate the influence of various specimen collection methods on the test results and further clarify the correlation with clinical practice.