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有关抗胆碱能药物治疗哮喘急性发作的效果报道不一,为了解在哮喘急性发作开始时,在吸入β肾上腺素能药物的基础上并用硫酸阿托品是否能增加支气管扩张作用,作者进行了研究观察。病人和方法 40例成年哮喘病人年龄18～65岁,均无吸烟、心脏病、青光眼、前列腺肥大、慢支肺气肿、商血压等病史。病人按双盲设计随机分成两组,一组单用二羟苯基异丙氨基乙醇喷雾(5%溶液3ml),另一组并用硫酸阿托品(2.5mg,溶在3ml生理盐水中),在2小时观察期内不用其它药物治疗。用药前及用药后30、60、120分钟分别测定肺功
The anticholinergic drugs for the treatment of acute exacerbation of asthma have reported different effects, in order to understand the onset of acute asthma, β-adrenergic drugs inhaled on the basis of combined with atropine sulfate can increase bronchiectasis, the authors observed the study . Patients and Methods 40 cases of adult asthma patients aged 18 to 65 years old, no smoking, heart disease, glaucoma, prostatic hypertrophy, chronic bronchitis, blood pressure and other business history. Patients were randomized in double-blind design to one of two groups: one was sprayed with dihydroxyphenyl isopropylaminoethanol (3 ml 5% solution) and the other was atropine sulfate (2.5 mg dissolved in 3 ml saline) Hours without observation of other drugs during the treatment. Lung function was measured before treatment and 30, 60, 120 minutes after treatment