目的探讨用苦瓜素对糖调节受损期防治的临床价值。方法于2003年12月至2006年8月对山西省朔州市中医院新诊断238例糖调节受损(JGR)者给予含服还原苦瓜素含片每次150mg,每日3次(为常规治疗剂量的一半),于治疗前、治疗6个月、12个月,分别测糖耐量加胰岛素兴奋实验(OGTT+INS-ST),以此评价其临床价值。结果经过治疗后,使 IGR 者血糖及胰岛素水平全部恢复至正常值。结论还原苦瓜素含片对 IGR 者疗效显著。 Objective To investigate the clinical value of momordicin in prevention and treatment of impaired glucose regulation. Methods From December 2003 to August 2006, 238 new cases of impaired glucose regulation (JGR) in Shuozhou Traditional Chinese Medicine Hospital of Shanxi Province were given buccal reduction of Momordicin 150mg three times a day Half of the treatment dose). The clinical value of OGTT + INS-ST was measured before treatment, 6 months and 12 months after treatment, respectively. Results After treatment, so IGR blood glucose and insulin levels were restored to normal. Conclusion Reduction of bitter gourd lozenges has a significant effect on IGR.