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本文观察了经腹腔注射四氯化碳（每次４００ｍｇ／ｋｇｂ．ｗ，每周三次）亚急性染毒大鼠注药１、２、３周时肝脏的超氧化物歧化酶、谷胱甘肽过氧化物酶活力及脂质过氧化物—丙二醛含量的变化，结果发现四氯化碳亚急性染毒大鼠肝脏中上述的抗氧化酶活性在三个时间组均比对照组低（Ｐ＜０．０１），同时，丙二醛含量均高于对照组（Ｐ＜０．０１及０．０５），提示四氯化碳亚急性染毒大鼠肝脏抗氧化酶活性受四氯化碳毒性所抑制，同时出现肝脏脂质过氧化并造成肝损害
This article observed the intraperitoneal injection of carbon tetrachloride (400mg / kgb.w each time, three times a week) subacute injection of 1, 2, 3 weeks after injection of the liver superoxide dismutase, glutathione Peroxidase activity and lipid peroxides - malondialdehyde content changes and found that carbon tetrachloride subacutely exposed rats liver antioxidant activity in the above three groups were lower than the control group ( P <0.01). At the same time, the content of malondialdehyde was higher than that of the control group (P <0.01 and P <0.01), which suggested that the activities of hepatic antioxidant enzymes in rats sub-acutely treated with carbon tetrachloride were affected by tetrachloride Carbon toxicity is inhibited, while liver lipid peroxidation and liver damage