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目的:针对抗生素应用不合理的因素进行分析研究,为抗生素在临床医学中的合理应用提供参考依据,降低对患者身体带来的损害。方法:随机选取2013年1月至2014年12月期间在我院住院的2000例患者的临床资料,统计其住院期间抗生素的应用情况,分析抗生素不合理应用的影响因素。结果:选取的2000份病例中,患者住院期间不舍理应用抗生素的为200例,不合理率为10%,其主要是由用药超出剂量、重复用药、与其他药物搭配使用不当等不合理问题,分别占37%、32.50%、17%。2000例患者中,1152例患者在临床治疗中应用一种抗生素治疗,658例患者在临床治疗中应用两种抗生素,190例患者在临床治疗中应用两种以上的抗生素。结论:抗生素的应用仍然存在着不合理的情况,医院应在今后的临床治疗中按照抗生素应用的相关规定和原则严格用药,降低临床医生对抗生素的不合理应用,提高医院抗生素的合理应用水平。
OBJECTIVE: To analyze the unreasonable factors of antibiotics and provide a reference for the rational application of antibiotics in clinical medicine, and to reduce the damage to the patients. Methods: The clinical data of 2000 patients hospitalized in our hospital from January 2013 to December 2014 were randomly selected. The application of antibiotics during hospitalization was analyzed. The influencing factors of unreasonable application of antibiotics were analyzed. Results: Among the 2000 selected cases, 200 cases were not treated with antibiotics during hospitalization, and the unreasonable rate was 10%. This was mainly caused by irrational problems such as overdose of medication, repeated medication, improper use with other drugs, etc. , Accounting for 37%, 32.50% and 17% respectively. Of the 2000 patients, 1152 patients were treated with one antibiotic in clinical trials, 658 patients were treated with two antibiotics in clinical trials and 190 patients were treated with two or more antibiotics in clinical trials. Conclusion: There are still some unreasonable application of antibiotics. Hospitals should strictly use antibiotics in the future clinical treatment according to the relevant regulations and principles of antibiotics to reduce the unreasonable application of antibiotics to clinicians and improve the rational use of antibiotics in hospitals.