吻合口瘘是食管、贲门癌切除,食管胃吻合术后较为常见且后果严重的并发症之一。国外文献报告吻合口瘘的发生率1.8%～22%,死亡率11.6%～53.9%;而国内报告吻合口瘘的发生率则为2.6%～6.4%,死亡率在38.1%～53.6%之间。近年来,随着医疗技术水平的不断提高,吻合口瘘的发生率和死亡率都有显著下降的趋势。1 吻合口瘘的发生原因 Anastomotic fistula is one of the common and serious consequences of esophageal and gastric cancer resection after esophagogastric anastomosis. Foreign literature reported that the incidence of anastomotic leakage was between 1.8% and 22%, and the mortality rate was 11.6% to 53.9%; while the incidence of anastomotic leakage in the country was 2.6% to 6.4%, and the mortality rate was between 38.1% and 53.6%. . In recent years, with the continuous improvement of the level of medical technology, the incidence of anastomotic leakage and mortality have significantly decreased. 1 Causes of anastomotic leakage