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目的:观察自拟益气养阴化瘀通络汤治疗糖尿病性视网膜病变的临床疗效.方法:选取72例糖尿病性视网膜病变患者按入院顺序随机分为两组各36例,对照组患者口服羟苯磺酸钙胶囊与甲钴胺片,观察组患者服用自拟益气养阴化瘀通络汤,方剂基本组方:枸杞、麦冬、山药、黄芪各20g,党参、玉竹、丹参、葛根各15g,茜草、白术、鸡内金各10g,黄连3g,加减方:阴虚火旺加龟版20g,地骨皮与玄参各10g;两组患者在上述治疗基础上均积极治疗基础疾病及糖尿病其他并发症,疗程2周,连续治疗2～3个疗程.治疗前后均进行眼底检查及视力检查,依据《实用眼科学》提出的评定标准对两组患者进行疗效评定.根据《中医眼科学》提出的评价标准对两组患者进行中医证候疗效评定.在两组患者治疗过程中,详细记录患者不良反应发生情况.结果:两组患者综合疗效评定结果显示,观察组患者治疗总有效率为94.44％,对照组患者治疗总有效率为77.78％,观察组疗效明显优于对照组(P＜0.05).两组患者中医证候疗效比较结果显示,观察组患者治疗总有效率为97.22％,对照组患者治疗总有效率为75.00％,观察组疗效明显优于对照组(P＜0.05).观察组患者2例(5.56％)患者恶心、呕吐,1例(2.78％)患者轻微腹痛;对照组患者2例(5.56％)恶心,1例(2.78％)食欲下降,两组患者不良反应无显著差异(P＞0.05).结论:对糖尿病性视网膜病变患者采用自拟益气养阴化瘀通络汤治疗,疗效显著,优于常规西医治疗,且不良反应发生率低,值得推广应用.“,”Objective:To observe clinical efficacy of diabetic retinopathy treated with Self-made Yiqi Yangyin Huayu Tongluo Decoction.Methods:72patients of diabetic retinopathy were randomly divided into two groups of 36patients,the controlled group of patients took dobesilate calcium capsules and tablets mecobalamin,the observed group of patients took Self-made Yiqi Yangyin Huayu Tongluo Decoction,the basic prescription:wolfberry,ophiopogon root,Chinese yam,Astragalus respectively 20g,Madder,Atractylodes,Gallus gallus respectively 15g,Coptis chinensis 10g,Coptis 3g,plus or minus side:WANG plus turtle shell 20g,cortex lycii radicis and scrophulariaceae 10g; the two groups of patients were treated with underlying disease and other complications of diabetes actively at the time based on the above treatment,treatment for two weeks,2 ～3course of continuous treatment.Fundus examination were performed before and after treatment and visual inspection,according to the evaluation criteria,Practical Ophthalmology raised two groups of patients assessed for efficacy.According to the evaluation criteria Chinese Ophthalmology raised two groups of patients with syndromes efficacy evaluation.Patients in both groups during treatment,a detailed record of the occurrence of adverse reactions in patients.Results:The comprehensive assessment of the efficacy of treatment of the two groups of patients showed,the total effective rate of the observation group was 94.44％,the total effective rate of the controlled group was 77.78％,the observation group were significantly better than the controlled group (P＜0.05).The efficacy of traditional Chinese medicine syndrome of the two groups of patients showed that the total effective rate of the observation group of patients was 97.22％,the total effective rate of the controlled group was 75.00％,the observation group were significantly better than the controlled group (P＜0.05).2patients (5.56％) of the observation group had nausea,vomiting,1case (2.78％)had mild abdominal pain; 2patients (5.56％)of the controlled group had nausea,1ease (2.78％)lost appetite,the adverse reactions of the two groups had no significant difference (P＞0.05).Conclusion:Patients with diabetic retinopathy treated with Self-made Yiqi Yangyin Huayu Tongluo Decoction,can get a significant effect,be superior to conventional western medicine,and the low incidence of adverse reactions,should be widely applied.