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目的探讨肺结核病发病的非生物学因素,为预防肺结核病提供科学依据。方法采用1∶1配对的病例-对照研究方法,统计分析应用单因素和多因素的Logistic回归分析法。结果单因素分析显示:已婚(OR=8.0,OR95%CI=1.8～34.8)、未接种卡介苗(OR=5.5,OR95%CI=1.9～15.9)、流动人口(OR=8.3,OR95%CI=4.0～17.2)、农村人口(OR=37.5,OR95%CI=9.2～152.6)和贫穷(OR=8.0,OR95%CI=3.4～18.7)等因素与肺结核发病有明显的相关性;多元回归分析则显示,已婚(OR=16.4,OR95%CI=1.5～183.7)、农村人口(OR=18.6,OR95%CI=3.7～94.4)和贫穷(OR=6.2,OR95%CI=1.4～27.6)与肺结核病的发病密切相关。结论已婚、农村人口和贫穷是影响肺结核发病的主要的非生物学因素。
Objective To investigate the non-biological factors of pulmonary tuberculosis and provide a scientific basis for the prevention of pulmonary tuberculosis. Methods 1: 1 paired case-control study, statistical analysis using single factor and multivariate Logistic regression analysis. Results Univariate analysis showed that the number of married persons (OR = 8.0, OR 95% CI = 1.8-34.8), non-vaccinated BCG (OR = 5.5, OR 95% CI 1.9- 15.9) (OR = 37.5, OR95% CI = 9.2-152.6) and poverty (OR = 8.0, OR95% CI = 3.4-18.7) were significantly associated with the incidence of pulmonary tuberculosis. Multivariate regression analysis (OR = 18.6, OR 95% CI = 3.7-94.4) and poverty (OR = 6.2, OR 95% CI = 1.4-27.6) were associated with tuberculosis (OR = 16.4, OR 95% CI 1.5-283.7) The incidence of the disease is closely related. Conclusion Married, rural population and poverty are the major non-biological factors that affect the incidence of tuberculosis.