患者女,67岁。左足拇趾屈侧肿物3年,于2014年4月11日来我院皮肤科门诊就诊。患者3年前无明显诱因左足拇趾屈侧出现一黄豆大丘疹,走路时有轻度疼痛,自行忍耐未诊治。该丘疹进行性增大,因长期走路压迫和摩擦逐渐变为扁平状并紧贴在拇趾屈侧面,病程中无破溃及渗液。既往高血压病史20年,常年口服硝苯地平(20 mg,每日2次),血压控制可,否认左足拇指有外伤史,婚育史无特殊,家族成员中无 Female patient, 67 years old. Left toe flexor mass 3 years, on April 11, 2014 to our hospital dermatology clinic. 3 years ago, there was no obvious incentive in patients with left toe flexor side of the soybean appeared a large papules rash, mild pain when walking, patiently patient without diagnosis and treatment. The papular progressive increase due to long-term walking pressure and friction gradually become flat and close to the flexor side of the flexor to flexion, ulcer disease and exudate. Previous 20 years of history of hypertension, perennial oral nifedipine (20 mg, 2 times a day), blood pressure control may be deny the history of trauma left thumb, history of marriage and childrens no special family members