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目的观察0.1%西吡氯铵含漱液对牙外伤纤维夹板固定术后菌斑形成的抑制作用。方法牙外伤患者40例随机分为2组,应用双盲法分别给予患者0.1%西吡氯铵含漱液漱口(试验组)或0.12%氯己定含漱液漱口(对照组)。每天5次,分别在晨起、睡前、三顿饭后各漱口1次,每次含15 mL,持续漱口60 s,漱口后1 h内禁饮食,7 d为一疗程。就诊当天(1 d)、4 d和8 d,按照Quigley-Hein指数(Turesky改良)测定菌斑指数。结果中期检查试验组和对照组菌斑指数组间比较差异无统计学意义(P>0.05);终点检查试验组和对照组菌斑指数组间比较差异无统计学意义(P>0.05)。结论 0.1%西吡氯铵含漱液可抑制牙外伤纤维夹板固定术后菌斑的形成,有利于牙周损伤的愈合。
Objective To observe the inhibitory effect of 0.1% cetylpyridinium chloride gargle on the plaque formation after tooth splint fixation. Methods Forty patients with dental trauma were randomly divided into two groups. Patients were given gargle with 0.1% cetylpyridate gargle (test group) or mouthwash with 0.12% chlorhexidine gargle (control group) by double-blind method. 5 times a day, respectively, in the morning, before going to bed, three meals after each mouthwash 1, each containing 15 mL, continued mouthwash 60 s, 1 h after swallowing banned diet, 7 d for a course of treatment. On the day of treatment (1 d), 4 d and 8 d, the plaque index was determined according to the Quigley-Hein index (Turesky’s improvement). Results There was no significant difference in the plaque index between the experimental group and the control group in the interim examination (P> 0.05). There was no significant difference in the plaque index between the experimental group and the control group (P> 0.05). Conclusions 0.1% cetylpyridinium gargle can inhibit the formation of plaque after dental plaque splint fixation, which is good for the healing of periodontal injury.