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以~(125)Ⅰ皮质醇放射免疫法测定了47例肺炎并心衰患儿血浆皮质醇浓度。其中男30例,女17例。结果:肺炎极期皮质醇平均为0.61±0.30μmol/L(223.64±110.96ng/ml),高于健康对照组0.47±0.15μmol/L(170.83±56.23ng/ml)。47例中皮质醇正常13例,升高27例,降低7例。降低组均为暴喘性肺炎。本研究提示:部分重症肺炎患儿下丘脑—垂体—肾上腺轴反应正常,能适应极期的应激反应,只有喘憋性肺炎患儿皮质醇水平降低。
Plasma cortisol levels in 47 children with pneumonia and heart failure were measured by ~ (125) Ⅰ cortisol radioimmunoassay. There were 30 males and 17 females. Results: The average level of cortisol in Pneumonia was 0.61 ± 0.30μmol / L (223.64 ± 110.96ng / ml), which was higher than that of the healthy control group (0.47 ± 0.15μmol / L) (170.83 ± 56.23ng / ml). 47 cases of normal cortisol in 13 cases, an increase of 27 cases, decreased in 7 cases. Reduce the group are asthmatic pneumonia. This study suggests that: part of children with severe pneumonia hypothalamic - pituitary - adrenal axis normal response to extreme stress response, only children with asthmatic pneumonia cortisol levels decreased.