乙型肝炎少儿患者与成人之间有一定的差异,α-干扰素对少儿患者的疗效尚未证实。作者对干扰素治疗患有慢性乙型肝炎伴肝功能异常少儿患者的安全性和有效性,作了多中心、多国籍、随机、双盲和对照研究。 病例入选标准:(1)年龄1～17岁; There are some differences between children with hepatitis B and adults, the efficacy of interferon-α in children has not been confirmed. The authors did a multicenter, multinational, randomized, double-blind, and controlled study of the safety and efficacy of interferon in children with chronic hepatitis B and liver dysfunction. Case selection criteria: (1) age 1 to 17 years old;