自19世纪末Thomas和Liser首先报道溃疡性结肠炎与肝胆病变有关以来,已有大量的研究证实溃结与肝胆疾病之间存在某种特殊关系。两者并存率各家报道不一。临床观察7～60%的溃结病人有肝功能异常;尸解资料40～50%的溃结有肝胆病变,有的高达96%;溃结手术中肝脏活检23～75%有病变;Kleckner选择性负压吸引肝穿刺84%有组织学上的改变。国内尚未有大宗的有关报道,结合文献,将溃结并发的主要肝胆病变综述如下: 一、胆管周围炎胆管周围炎占选择性溃结病人肝活检的30～50%。全结肠和次全结肠炎的病人比局 Since the late 19th century Thomas and Liser first reported that ulcerative colitis and hepatobiliary disease has been related to a large number of studies have confirmed that there is a special relationship between the ulcer and liver and gallbladder disease. Coexistence between the two reported different. Clinically observed in 7 to 60% of patients with ulceration have liver dysfunction; autopsy data 40 to 50% of the ulceration with hepatobiliary disease, and some as high as 96%; ulcer surgery liver biopsy 23 to 75% of lesions; Kleckner choice Negative pressure to attract liver puncture 84% of the histological changes. There is no large domestic relevant reports, combined with the literature, the main complications of ulceration complicated hepatobiliary lesions are summarized as follows: First, the bile duct peribiliary inflammation accounted for 30-50% of patients with selective ulceration of liver biopsy. Total colon and sub-total colitis patients ratio