论文部分内容阅读
大肠癌的化疗可分为两种:一是与手术并用的辅助化疗;另一是和恶性淋巴瘤、白血病同样癌的化学疗法。欧美大肠癌较多,对其手术后并用化疗的效果,曾进行相当严格的研究,很多方面值得参考,故略作介绍。 1957年美国的大学组(University Group)术中应用噻替哌0.4mg/kg,经门静脉与腹腔内给药,术后头2日每日再给0.2mg/kg。结果是无淋巴结转移者和女性患者5年生存率经统计学处理比对照组有明显提高。 1962年美国V.A医院组开始应用5—FU共同研
Colorectal cancer chemotherapy can be divided into two types: First, adjuvant chemotherapy with surgery; the other is the same chemotherapy as malignant lymphoma, leukemia. In Europe and the United States, there are many colorectal cancers. The effect of postoperative chemotherapy combined with chemotherapy has been studied quite rigorously. Many aspects are worthy of reference, so a brief introduction is given. In 1957 the United States University Group (University Group) intraoperative application of thiotepa 0.4mg/kg, via the portal vein and intraperitoneal administration, after the first two days after the surgery to give 0.2mg/kg. As a result, the 5-year survival rate of patients without lymph node metastasis and female patients was statistically improved compared with the control group. In 1962, V.A hospital group in the United States began to use 5-FU for joint research