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对 51 例卵巢良、恶性肿瘤和 28 例对照者的血清进行癌抗原 125( C A125 )、癌抗原 153( C A153)、铁蛋白( S F)、乳酸脱氢酶( L D H)和碱性磷酸酶( A K P)5 项指标检测。结果:(1)卵巢恶性肿瘤患者血清各项指标均值全部高于对照者和卵巢良性肿瘤患者( P< 0.05 或 P< 0.01);(2)Ⅲ、Ⅳ期卵巢癌患者各项指标阳性率高于Ⅰ、Ⅱ期患者( P< 0.05 或 P< 0.01);除 A K P外,上皮性癌患者各项指标阳性率高于非上皮性癌患者( P< 0.05);(3)判断卵巢肿瘤的良、恶性,单项指标以 C A125的诊断性能最好;多项指标组合以 C A125、 C A153、 S F 中任意 2 项同时增高作为阳性标准诊断性能最好。
Carcinoembryonic antigen 125 (C A125), cancer antigen 15 3 (C A15 3), ferritin (SF), and lactate dehydrogenase (LD) were detected in 51 cases of ovarian benign and malignant tumors and 28 controls. H) and alkaline phosphatase (AKP) 5 indicators detected. Results: (1) The mean values of serum markers in ovarian cancer patients were all higher than those in controls and ovarian benign tumors (P<0.05 or P<0.01); (2) Various ovarian cancer patients in stage III and IV The positive rate of the index was higher in patients with stage I and II (P<0.05 or P<0.01); the positive rate of each index in patients with epithelial carcinoma was higher than that in non-epithelial carcinoma except A K P (P<0). .05); (3) To judge the benign and malignant ovarian tumors, the single index with the best diagnostic performance of C A125; a number of indicators combined with any two of C A125, C A15 3, S F as a positive standard The best diagnostic performance.