目的探讨幽门螺杆菌(Hp)感染密度与14C尿素呼气试验(14C-UBT)检测值的关系。方法选择我院118例14C-UBT检查阳性患者,所有患者均取胃黏膜病理切片改良Giemsa染色,并按悉尼标准进行分析,比较病理组织学Hp的密度半定量值与14C-UBT检测值之间的关系。结果胃黏膜切片病理组织学检查,不同Hp密度患者14C-UBT检测值间差异有统计学意义(F=3.06,P<0.05)。结论Hp的密度与14C-UBT检测值高低有关,14C-UBT检测值在一定程度上可反映Hp感染的严重程度。 Objective To investigate the relationship between the density of Helicobacter pylori (Hp) infection and the 14C urea breath test (14C-UBT). Methods 118 patients with positive 14C-UBT in our hospital were enrolled. All patients were examined by modified Giemsa staining of gastric mucosa and analyzed according to Sydney standard. The histopathological Hp density between semi-quantitative and 14C-UBT was compared Relationship. Results There were significant differences in 14C-UBT values ​​between gastric mucosal sections and Hp density (F = 3.06, P <0.05). Conclusion The density of Hp is related to the level of 14C-UBT. The 14C-UBT can reflect the severity of Hp infection to a certain extent.