肿瘤的免疫治疗是在充分理解机体免疫原理的基础上,应用免疫学的手段提高肿瘤细胞的免疫源性和对杀伤细胞的敏感性,同时增强机体的抗肿瘤免疫应答效应。现已成为继手术治疗、放化疗和靶向治疗之后的另一种控制肿瘤的有效疗法,并广泛应用于临床。目前,抗肿瘤特异性单克隆抗体治疗、过继性免疫细胞回输治疗、抗肿瘤疫苗和免疫检查点抑制剂单克隆抗体治疗等多种方式的免疫治疗已被应用于临床,并取得了令人振奋的疗效。其中,免疫检查点抑制剂的单抗治疗因在临 Tumor immunotherapy is based on the full understanding of the body’s immune principles, the use of immunological means to improve the immunogenicity of tumor cells and the sensitivity of killer cells, while enhancing the body’s anti-tumor immune response. It has become another effective control of tumor after surgical treatment, chemoradiotherapy and targeted therapy, and has been widely used clinically. At present, various methods of immunotherapy have been applied in clinic, such as anti-tumor specific monoclonal antibody treatment, adoptive immune cell reinfusion therapy, anti-tumor vaccine and monoclonal antibody therapy of immune checkpoint inhibitor, and have achieved remarkable results Exciting effect. Among them, the immune checkpoint inhibitor monoclonal antibody therapy in progress