氟砷均为全身性毒物 ,对机体各器官组织均有损害 ,氟砷均已被肯定为生殖毒物[1- 2 ] ,但有关对子代生殖系统影响的研究十分有限。为探讨氟砷联合作用对子代睾丸损害影响 ,我们采用两代一窝繁殖试验的方法[3] ,对氟砷联合染毒大鼠子代睾丸进行了电镜观察 ,以期从超微病理角度探? Both fluoride and arsenic are systemic toxicants, which damage the organs and organs of the organism. Both fluorine and arsenic have been affirmed as reproductive toxicants [1-2], but the research on the influence on reproductive system of offspring is very limited. To explore the joint effects of fluoride and arsenic on testicular damage of progeny, we used two generations of a litter breeding test method [3], the testis of the offspring of rats exposed to fluoride and arsenic combined with electron microscopy was observed in order to explore from the ultra-pathological point of view ?