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探讨不同海拔高原低氧环境对重体力劳动者劳动能力的影响，研究以工地筑路民工为对象。采用荧光技术测定海拔２２６０ｍ移居３６００ｍ、５０５０ｍ筑路民工在重体力劳动负荷下全血５─—羟色胺的变化。随着海拔的升高，氧分压下降，筑路工劳动时间和劳动强度均与２２６０ｍ筑路工相等。但劳动效率明显降低，全血５一羟色胺含量梯度增高。移居３６００ｍ、５０５０ｍ筑路工二组与２２６０ｍ比较ｔ分别为２．３８和３．１８，Ｐ均＜０．０１。结论：高原低氧加之重体劳动是导致全血５一羟色胺单胺递质变化的主要因素。
To explore the impact of different altitude hypoxia on the labor ability of heavy manual workers, the study of road construction workers for the target. Fluorescence technique was used to measure the change of 5-HT in whole blood under heavy physical work load. As the altitude increases, the partial pressure of oxygen drops, the time and labor intensity of road workers are equal to that of 2260m road workers. However, labor efficiency was significantly reduced, 5-HT serotonin levels increased. Immigrants 3600m, 5050m road construction workers two groups compared with 2260m t were 2.38 and 3.18, P <0.01. Conclusion: Hypoxia combined with heavy labor is the main factor leading to the change of 5-hydroxytryptamine monoamine neurotransmission in whole blood.