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目的 :探讨结膜印迹细胞学检查 (CIC)在干眼诊断中的作用。方法 :对 45人 90眼正常组和 80人16 0眼实验组除采用泪液分泌实验I(S -I-T)、泪膜破裂时间 (BUT)、虎红染色 (RBS)及荧光素染色 (FLS)计分等常用眼表泪功能检查外 ,重点采用CIC ,通过观察结膜上皮细胞情况及杯状细胞数来了解正常眼、干眼的泪膜粘液层的情况。结果 :印迹细胞学分级及杯状细胞数组间均有显著的差异 ,正常组分级主要集中于 0级 ;非SS干眼组的分级主要集中于 1级和 2级 ;SS干眼组的分级主要集中于 2级及 3级。杯状细胞与虎红色计分呈负相关。结论 :结膜印迹细胞学检查通过分级、观察杯状细胞数变化 ,了解泪膜粘液层的情况可用于区分正常人与干眼症患者并可了解干眼的病程变化
Objective: To investigate the role of conjunctival imprinting cytology (CIC) in the diagnosis of dry eye. Methods: Ninety-five eyes of 90 eyes and 80 eyes of 160 eyes were divided into two groups by S-IT, BUT, RBS and FLS. Scoring and other common ocular surface tear function tests, focusing on the use of CIC, through the observation of conjunctival epithelial cells and goblet cells to understand the normal eye, dry eye tear film mucus layer. Results: There was a significant difference between the grading of cytology and goblet cell array. The grading of normal group was mainly on grade 0; the grading of non-SS dry eye group was mainly on grading 1 and 2. The grading of SS dry eye group was mainly Focus on Level 2 and Level 3. Goblet cells were negatively correlated with tiger red score. CONCLUSIONS: The conjunctival imprinting cytology examines the changes in goblet cell numbers by grading to understand the condition of the tear film mucus layer and can be used to differentiate between normal and dry eye patients and to understand the course of dry eye disease