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目的 :探讨石棉工人肺功能损害的最敏感指标。方法 :对某石棉制品厂石棉工人和石棉肺患者分别于 1984、1989及 1994年进行了三次的肺功能 (VC、 FVC、FEV1 、 FEV1 %、DLCO和 RV/TL C% )追踪观察。结果 :两组均随接尘时间的增长 ,肺通气功能 (VC、 FVC、FEV1 及 FEV1 % )和弥散功能 (DLCO)进行性损害 ;石棉肺患者弥散功能的进行性损害快于石棉工人 ;从变化值上看 ,下降速度较大的指标为 DLCO和 FVC。结论 :石棉工人肺功能变化的最敏感指标为 FVC和 DLCO。
Objective: To investigate the most sensitive indicators of lung function impairment in asbestos workers. Methods: Lung function (VC, FVC, FEV1, FEV1%, DLCO and RV / TL C%) was tracked three times in asbestos workers and asbestosis patients in a asbestos product factory in 1984, 1989 and 1994, respectively. Results: The lung function (VC, FVC, FEV1 and FEV1%) and diffuse function (DLCO) were all impaired with the increase of dusting time. The progress of diffuse function in asbestosis patients was faster than asbestos workers. Changes in value point of view, a larger decline in the indicators for the DLCO and FVC. Conclusion: The most sensitive indicators of pulmonary function in asbestos workers are FVC and DLCO.