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养心液为人参、麦冬、三七、法半夏、茯苓等药的水煎醇沉剂。本文观察了给戊巴比妥麻醉犬静脉注射0.25g/kg养心液后的血液动力学的变化情况。结呆:给药后MAP、LVEDP无明显变化,HR有所减慢,LVSP、±dp/dtmax、CO、SI,CI、LVWI及CBF均明显升高,TPR则显著下降。作用维持5min,至10min时基本恢复至给药前水平。提示:养心液静脉注射能增强麻醉犬心肌收缩与舒张性能,能扩张冠脉,增加冠脉血流量,降低总外周血管阻力和后负荷,使心输出量增加,改善心脏泵血功能。
The nourishing liquid is a water-decoction and alcohol-reducing agent for ginseng, Ophiopogon japonicus, Panax notoginseng, Pinellia tuberculosis, and peony. In this paper, we observed the hemodynamic changes in pentobarbital anesthetized dogs after intravenous injection of 0.25 g/kg of cardiotonic fluid. Nodules: no significant changes in MAP, LVEDP after administration, HR slowed, LVSP, ± dp/dtmax, CO, SI, CI, LVWI and CBF increased significantly, TPR decreased significantly. The effect was maintained for 5 min, and it returned to the pre-dose level until 10 min. Tip: Intravenous injection of Yangxin can enhance myocardial contractility and diastolic performance in anesthetized dogs, expand coronary artery, increase coronary blood flow, reduce total peripheral vascular resistance and afterload, increase cardiac output and improve cardiac pump function.