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目的回顾分析2004年4月~2005年5月830例注射狂犬疫苗后抗体检测结果。方法用间接酶联免疫吸附法测血清抗体,自动酶标仪定性。被检对象分为12岁以下组、13~30岁、31~60岁组和61岁以上组。结果全部被检对象阳性率75.9%,国产疫苗阳性率高于进口疫苗,不同年龄组间差异无显著性。进口疫苗注射后检测弱阳性者一周内加强注射2针59%转阳,国产疫苗100%转阳。结论疗程内换用不同品牌疫苗对抗体的产生影响不大,国产疫苗效果好于进口疫苗。
Objective To retrospectively analyze the antibody test results after 830 rabies vaccine injections from April 2004 to May 2005. Methods Serum antibodies were detected by indirect enzyme - linked immunosorbent assay. Subjects under the age of 12 were divided into groups, 13 to 30 years old, 31 to 60 years old group and 61 years old group. Results The positive rate of all subjects was 75.9%, the positive rate of domestic vaccine was higher than that of imported vaccine, and there was no significant difference between different age groups. Imported vaccines to detect weak positive after a week of intensive injection of 2 needles 59% turn positive, domestic vaccine 100% turn positive. Conclusion The course of treatment with different brands of vaccines on the production of antibodies has little effect, domestic vaccine effect is better than imported vaccine.