为了解四川省健康人群白喉、百日咳、破伤风的免疫状况 ,及时为免疫策略提供依据 ,2 0 0 1年对成都等 6个市897名健康者进行了白喉、百日咳、破伤风抗体水平监测。结果显示 :在监测的 4个年龄组中 ,白喉、破伤风抗毒素保护率均 >80 % ,其中 2～ 4岁、5～ 9岁、10～ 14岁白喉、破伤风抗毒素保护率均 >95 % ;2～ 4岁、5～ 9岁、10～ 14岁百日咳抗体几何平均滴度 (GMT)≥ 1:6 4 2 ,保护率均 >75 % ,≥ 2 5岁的百日咳抗体GMT为 1:80 ,保护率2 8 2 1%。按现行的儿童免疫程序接种百白破联合疫苗和白破联合疫苗已收到良好效果 ,对白喉、破伤风、百日咳已经形成了较好的免疫屏障 ,但成人的百日咳免疫力还需提高 In order to understand the immune status of diphtheria, whooping cough and tetanus in healthy population in Sichuan Province and provide the basis for the immunization strategy in time, the level of diphtheria, pertussis and tetanus antibody was monitored in 897 healthy people in 6 cities of Chengdu in 2001. The results showed that the protective rates of diphtheria and tetanus antitoxin in the four age groups were> 80%, of which the protection rates of diphtheria and tetanus antitoxin between 2 to 4 years old, 5 to 9 years old and 10 to 14 years old were both> 95% ; GMT (1: 642) of 2 to 4 years old, 5 to 9 years old, 10 to 14 years of age who had pertussis antibody was> 75%, GMT of whooping cough antibody ≥ 25 years old was 1:80 , Protection rate 2 8 2 1%. Inoculation of Baibabuo combination vaccine and Baibuai combination vaccine according to the current childhood immunization program has received good results and has formed a good immune barrier to diphtheria, tetanus and pertussis, but the immunity of adults needs to be improved