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目的:评价卡前列素氨丁三醇对高危剖宫产孕妇产后止血的临床疗效。方法:选取2014年1月—2015年12月间收治的分娩产妇94例,依据其先后住院顺序的不同分为对照组和观察组,每组47例;其中对照组孕妇于胎儿娩出后立即给予缩宫素各10 U,静脉滴注、宫体注射和1 mg卡前列甲酯栓口含治疗;观察组孕妇则予采用10 U缩宫素静脉滴注,以及250μg卡前列素氨丁三醇注射液宫体注射;比较两组患者产后出血量、尿量和不良反应的发生率。结果:观察组孕妇无论是术中还是产后2和24 h出血量明显少于对照组(P<0.05);观察组孕妇无论是术中还是产后2和24 h尿量均明显多于对照组(P<0.05);观察组孕妇手术后24 h不良反应的发生率为4.25%显著低于对照组为25.53%(P<0.05)。结论:采用卡前列素氨丁三醇防治高危剖宫产孕妇产后止血的临床疗效较为显著,不良反应的发生率较低。
Objective: To evaluate the clinical effect of carboprost trometamol on postpartum hemostasis in high-risk cesarean section pregnant women. Methods: Ninety-four cases of childbirth admitted between January 2014 and December 2015 were divided into control group and observation group according to the sequence of hospitalization, 47 cases in each group. The pregnant women in the control group were given immediately after the fetus was delivered Oxytocin each 10 U, intravenous infusion, intrauterine injection and 1 mg card forefront of methyl ester embolism with treatment; observation group pregnant women were given 10 U oxytocin intravenous infusion, and 250 μg of carboplatin trometamol Injection of uterine body injection; comparison of postpartum hemorrhage volume, urine output and incidence of adverse reactions in both groups. Results: The bleeding volume in observation group was significantly less than that in control group both at 2 and 24 h after operation (P <0.05). The urine output of observation group was significantly higher than that of control group at 2 and 24 h postoperatively P <0.05). The incidence of adverse reactions in pregnant women at 24 hours after operation was 4.25%, which was significantly lower than that in the control group (25.53%, P <0.05). Conclusion: The clinical effect of applying carboprost trometamol to prevent and treat postpartum hemostasis in high-risk cesarean section pregnant women is significant, and the incidence of adverse reactions is low.