去年,有10例婴儿因患以往未被认识的新的疾病而住院。此病以脑病的急性发作、发烧、休克、水样泻、严重的弥漫性血管内凝血(DIC)和肾脏、肝脏功能障碍为特征。这些婴儿中7例死亡。尚未发现特异性病原,但初步研究提示此病的病理生理学改变可能包括蛋白分解酶(如胰蛋白酶)释放入血循环并伴有微循环障碍。作者称此病为出血性休克和脑病综合征(HSE)。 Last year, 10 infants were hospitalized for new diseases that they had not previously known. The disease is characterized by an acute episode of encephalopathy, fever, shock, watery diarrhea, severe diffuse intravascular coagulation (DIC), and renal and hepatic dysfunction. Seven of these infants died. No specific pathogen has been found yet, but preliminary studies suggest that pathophysiological changes may include the release of proteolytic enzymes such as trypsin into the bloodstream with microcirculation. The authors call the disease hemorrhagic shock and encephalopathy syndrome (HSE).