胆石症是一种影响人类健康的常见病,据统计,发病率约占10％。近年来,发现给胆固醇胆石症患者服用鹅脱氧胆酸(Chenodeoxycholic acid,简称CDCA),能使胆石逐渐溶解,此后,陆续有临床报道。 CDCA与其它胆汁酸一样,是以和甘氨酸或牛磺氨酸相结合的形式,存在于人或畜禽胆汁中,在人胆汁占45％,为含量最高的一种胆汁酸,在肝细胞中由胆固醇合成。理化性质 Cholelithiasis is a common disease affecting human health, according to statistics, the incidence rate of about 10%. In recent years, it has been found that taking cholinesterase (Chenodeoxycholic acid, CDCA) for patients with cholesterol cholelithiasis can gradually dissolve the gallstones, and then one after another clinical reports. Like other bile acids, CDCA is present in human or animal bile in combination with glycine or taurine, and is found in 45% of human bile, the highest content of a bile acid in hepatocytes From cholesterol synthesis. Physical and chemical properties