曾报道了以铁卟啉作为细胞色素Ｐ４５０模拟酶的活性中心，轴向配体例如巯基苯甲酸、半胱氨酸作为激活剂，提高模拟酶体系催化活性的研究．而过氧化氢酶的活性中心也为铁卟啉．进一步报道模拟酶的轴向配体提高过氧化氢酶的活性，并提出了一种提高天然酶活性的新方法．硫代硫酸钠、维生素Ｃ、巯基乙酸和Ｌ－半胱氨酸可作为过氧化氢酶的轴向配体，而激活过氧化氢酶． It has been reported that the iron porphyrin as a cytochrome P450 mimic enzyme activity center, axial ligands such as mercaptobenzoic acid, cysteine ​​as an activator to improve the activity of mimic enzyme system research. The catalase activity center is iron porphyrin. Further reports that mimic axial ligands increase catalase activity and propose a new method to increase native enzyme activity. Sodium thiosulfate, vitamin C, thioglycolic acid and L-cysteine ​​act as axial ligands for catalase and activate catalase.